amcHydroFlow HP--American Membrane Corporation

SELECT BY INDUSTRY

PRODUCT TYPES

FILTER MEDIA

amcHydroFlow HP

amcHydroFlow HP cartridge is a precision filter specifically constructed to provide high flow rate and retention. The filter medium is amcAccupor membrane (modified hydrophilic polyethersulfone membrane) developed by AMC for rigorous operating conditions in a variety of filtration applications.

amcHydroFlow HP cartridge is designed for final filtration when absolute retention is required, or prefiltration where highly fine particle removal is desired to protect the final filter.

Each cartridge is flushed with appropriate solvents to provide optimum cleanliness, and integrity tested to verify compliance with established pore size specifications.

amcHydroFlow HP cartridge is compatible with autoclave and in-line steam sterilization, as well as chemical sanitization methods that makes it an ideal microporous membrane cartridge for various applications.

Performance Advantages

Constructed of only two materials, i.e., modified polyethersulfone and polypropylene with no adhesives to ensure lower extractables
All components meet USP Class VI-121°C Plastics Tests for biosafety, and are listed as being acceptable for food contact applications according to the Code of Federal Regulations, Title 21
Provides high flow rate and particle retention
Available in a variety of configurations allowing for easy installation in commonly used filtration systems
100% integrity tested during manufacturing to assure product reliability and quality

Typical Applications

Parenterals, ophthalmics, oral and topical medicines, serum, tissue culture media, wash and rinse water, diagnostic reagents, buffers, vaccines, bottle and vial washers, make-up water

Materials of Construction
Filter Media:	Single layer of pleated amcAccupor membrane (modified hydrophilic PES membrane)
Support Material:	Polypropylene
Structure Components:	Polypropylene
Sealing Technology:	Thermal bonding

Dimensions
Nominal Length:	10, 20, 30, and 40 inch (25.4, 50.8, 76.2, and 101.6 cm)
Diameter:	2.7 inches (6.9 cm)

Nominal Pore Sizes	0.03, 0.1, 0.2, 0.45, 0.65, 0.8, 1.2 μm

Typical Effective Filtration Area	7 ft² (0.65 m²) per 10 inch

Maximum Operating Temperature	90°C (194°F) at 30 psi (2.1 bar)
(Supported adapters are recommended for applications at elevated temperature over 60°C)

Sterilization/Sanitization Methods
Chemical:	peracetic acid, chlorinated alkaline products, bleach, sulfur dioxide, and hydrogen peroxide at typical sanitization concentrations and temperatures
Hot Water:	88°C (190°F) at 5 psi (0.34 bar)
Autoclave:	121°C (250°F) for 30 minutes up to 50 cycles
In-line Steam:	140°C (284°F) for 60 minutes at 2 psi (0.14 bar) up to 25 cycles

Maximum Differential Forward Pressure	0.03 μm, 0.1 μm, 0.2 μm, 0.45 μm, 0.65 μm: 60 psi (4.1 bar) at ambient temperature 0.8 μm, 1.2 μm: 50 psi (3.4 bar) at ambient temperature

Maximum Differential Back Pressure	15 psi (1.0 bar) at ambient temperature

Maximum Continuous Pressure	Limited by housing

Recommended Integrity Tests

Minimum Bubble Point:	0.03 μm: 38 psi (2.7 bar) - ethanol 0.1 μm: 28 psi (2.0 bar) - ethanol 0.2 μm: 49 psi (3.4 bar) - water 0.45 μm: 32 psi (2.3 bar) - water 0.65 μm: 22 psi (1.5 bar) - water 0.8 μm: 12 psi (0.8 bar) - water 1.2 μm: 6 psi (0.4 bar) - water

Diffusional Flow in Water:	Provided separately*

Typical Water Flow Rate	0.03 μm: 0.3 gpm/psi/10 inch length (1.7 lpm/0.1 bar/25.4 cm length) 0.1 μm: 1.2 gpm/psi/10 inch length (6.6 lpm/0.1 bar/25.4 cm length) 0.2 μm: 3 gpm/psi/10 inch length (16.5 lpm/0.1 bar/25.4 cm length) 0.45 μm: 5.2 gpm/psi/10 inch length (28.5 lpm/0.1 bar/25.4 cm length) 0.65 μm: 6.8 gpm/psi/10 inch length (37.4 lpm/0.1 bar/25.4 cm length) 0.8 μm: 10 gpm/psi/10 inch length (54.9 lpm/0.1 bar/25.4 cm length) 1.2 μm: 13 gpm/psi/10 inch length (71.5 lpm/0.1 bar/25.4 cm length)

Oxidizable Substances	Filtrate meets USP XXll requirements for purified water with <1 L flush after autoclaving

Biosafety	All components meet USP Class VI-121°C Plastics Tests, and are listed as being acceptable for food contact accoding to the Code of Federal Regulations, Title 21

Endotoxin Level	<0.25 EU/ml utilizing Limulus Amoebocyte Lysate (LAL) test

Typical Resistivity Recovery to 18 megaohm-cm	35 gallons (133 L)

Bacterial Retention	Provided Upon Request

Typical Water Flow Rate

amcHydroFlow HP Water Flow Rate

Ordering Information H F ■ ■ H ◆ ● ▲
■ Rated Pore Size	03	0.03 μm
	10	0.1 μm
	20	0.2 μm
	45	0.45 μm
	65	0.65 μm
	80	0.8 μm
	12	1.2 μm

◆ Nominal Length	1	10 inch (25.4 cm)
	2	20 inch (50.8 cm)
	3	30 inch (76.2 cm)
	4	40 inch (101.6 cm)

● Cartridge Configuration	D	SOE, Flat
	F	DOE, Gasket/Gasket 10 inch increments
	J	SOE, -222/Flat/SS*
	K	SOE, -222/Fin/SS*
	M	SOE, -222/Flat
	P	SOE, -222/Fin
	Q	SOE, -226/Fin
	R	SOE, -226/Fin/SS*
	V	SOE, -226/Flat
	W	SOE, -226/Flat/SS*

▲ Seal Material	S	Silicone
	V	Viton
	E	Ethylene Propylene

amcHydroFlow HP.pdf

amcHydroFlow HP Validation Guide.pdf